Mounjaro (Tirzepatide) for Women in Singapore: Efficacy, Safety & What to Know
Doctor-reviewed guide to tirzepatide for women's weight loss — clinical results, hormonal considerations, and comparison with semaglutide.
At a glance
- Tirzepatide (Mounjaro) has produced the highest weight loss results in clinical trials — an average of 21% body weight at the maximum dose.
- For women struggling with weight, these results represent a significant advance.
- This guide covers women-specific aspects of tirzepatide treatment.
Introduction
Tirzepatide (Mounjaro) has produced the highest weight loss results in clinical trials — an average of 21% body weight at the maximum dose1. For women struggling with weight, these results represent a significant advance. This guide covers women-specific aspects of tirzepatide treatment.

Why Tirzepatide Stands Out for Women
Tirzepatide's dual GLP-1/GIP mechanism offers women several advantages:
- Superior weight loss — average 21% vs ~15% for semaglutide1
- Improved insulin sensitivity — particularly beneficial for women with PCOS
- Metabolic improvements — blood pressure, lipids, and inflammatory markers
- Potentially better GI tolerability — some studies suggest lower nausea rates than semaglutide
Women in SURMOUNT Trials
Women comprised approximately 67% of SURMOUNT-1 participants. Key findings:
- Women achieved weight loss comparable to the overall population
- No gender-specific safety concerns identified
- Improvements in metabolic health markers were consistent across genders
- Dose-response relationship was maintained in women
Women-Specific Considerations
The same hormonal considerations apply to tirzepatide as to semaglutide.
Contraception
Tirzepatide delays gastric emptying and may affect oral contraceptive absorption. Women on the pill should discuss alternative contraception with their doctor.
Pregnancy
Contraindicated during pregnancy. Stop tirzepatide before trying to conceive — follow your doctor's guidance on timing (typically at least 2 months).
PCOS
The insulin-sensitising effects of tirzepatide may be particularly beneficial for women with PCOS, though specific PCOS trials are ongoing(Based on MOH guidelines and prescribing information).
Cost in Singapore (SGD)
GLP-1 receptor agonist medications for weight management in Singapore typically cost SGD $200–500 per month depending on the specific medication and dosage. zoey™ offers structured weight management plans with ongoing doctor oversight and support.
Prices are approximate and may vary. Updated April 2026.
FAQ
Clinical data suggests greater average weight loss with tirzepatide vs semaglutide. Your zoey™ doctor will recommend the best option based on your specific profile.
GI side effects are common with both medications. Some data suggests Mounjaro may have somewhat lower nausea rates, but individual responses vary.
Yes, and it may be particularly beneficial. The dual mechanism improves insulin sensitivity, a core issue in PCOS.
Mounjaro has HSA registration. Availability may vary due to global supply. Your zoey™ doctor can advise on current access.
Mounjaro is similarly priced to Wegovy (S$400–650/month), though pricing varies by dose and supply.
References
- → Return to pillar: Complete Guide to Medical Weight Loss for Women
This article is for informational purposes only and does not constitute medical advice. Always consult a licensed doctor before starting any treatment.