For a comprehensive guide to birth control, see our complete guide.
Medically reviewed by Dr. Kevin Chua, Medical Director
Disclaimer: This article provides general medical information and is not a substitute for professional medical advice. Always consult a licensed doctor before starting any contraception.
"The pill" isn't one thing. There are over a dozen oral contraceptive formulations available in Singapore, and the differences between them matter more than most women realise. The wrong pill can cause months of unnecessary side effects; the right one can clear acne, ease period pain, and protect against pregnancy all at once.
This guide breaks down every type available — combined pills, progestogen-only pills, different generations of progestogen — and explains how to think about the choice.
Combined pills contain both synthetic oestrogen (ethinyloestradiol) and a progestogen. They prevent pregnancy primarily by suppressing ovulation.
How they work: 1. Suppress ovulation (primary mechanism) 2. Thicken cervical mucus (prevents sperm from reaching eggs) 3. Thin the endometrium (reduces likelihood of implantation)
Efficacy: 99.7% with perfect use; ~93% with typical use
POPs contain no oestrogen — only a progestogen. They work mainly by thickening cervical mucus and thinning the endometrium. Some (particularly desogestrel-based ones) also suppress ovulation.
Suitable for women who cannot take oestrogen: - Smokers over 35 - Women with migraines with aura - Breastfeeding women (oestrogen can reduce milk supply) - Women with certain cardiovascular risk factors - Women with oestrogen-sensitive conditions
The "generation" of a combined pill refers to the progestogen component. Different progestogens have different profiles — including how androgen-like they are, which affects side effects like acne, mood, and libido.
| Generation | Progestogen | Example Brands | Notes |
|---|---|---|---|
| 1st gen | Norethisterone | Some older formulations | Higher androgenic activity |
| 2nd gen | Levonorgestrel | Microgynon 30, Nordette | Reliable; slightly androgenic |
| 3rd gen | Desogestrel, Gestodene | Marvelon, Mercilon, Femodene | Lower androgenic; slightly higher DVT risk than 2nd gen |
| 4th gen | Drospirenone | Yasmin, Yaz | Anti-androgenic; good for acne, PMDD |
| Cyproterone acetate | Diane-35 | Highly anti-androgenic; used specifically for acne/hirsutism | Not considered a standard contraceptive in all guidelines |
Higher androgenic progestogens may worsen acne and increase sebum production.
Anti-androgenic progestogens (drospirenone, cyproterone) often improve acne, reduce hirsutism, and may help with PMS.
Different life situations call for different formulations.
Choose a pill with anti-androgenic progestogen: - Yasmin or Yaz (drospirenone) — most commonly prescribed for acne - Diane-35 (cyproterone acetate) — highly anti-androgenic; specifically used for acne/hirsutism - Allow 3–6 months to see skin improvements
→ More detail: Birth Control and Acne (SG-Z-BC-08)
| Combined Pill | POP (Traditional) | POP (Desogestrel) | |
|---|---|---|---|
| Take at same time | Recommended but some flexibility | Within 3 hours | Within 12 hours |
| Missed pill rule | 12+ hours late = missed | 3+ hours late = use backup | 12+ hours late = use backup |
| Start protection | Day 1–7 depending on cycle day started | 48 hours after starting | 48 hours after starting |
The first 3 months are an adjustment period. Common experiences include:
Most side effects that are going to resolve do so within 3 months. If problems persist beyond that, your zoey™ doctor can recommend a different formulation.
Oral contraceptive pills in Singapore typically cost SGD $20–50 per month depending on the brand and formulation. Generic options are available at the lower end of this range.
Prices are approximate and may vary. Updated April 2026.
There's a best pill for you, which depends on your health history, skin, cycle goals, and side effect sensitivities. Your zoey™ doctor assesses all of these to recommend the most suitable formulation.
Yes. Switching is straightforward — your zoey™ doctor can advise on timing and whether a bridge period of backup contraception is needed.
Depends on when in your cycle you start. Starting on day 1 of your period: effective immediately. Starting on any other day: use backup contraception for 7 days. Your zoey™ doctor will advise on the specific protocol for your situation.
Yes. Long-term use of oral contraceptives is well-supported by evidence. Benefits including reduced ovarian and endometrial cancer risk actually increase with duration of use. Annual review with your doctor is appropriate.
Some corporate medical plans cover GP consultations that include contraceptive prescriptions. The medication itself may or may not be covered. MediSave does not cover routine contraception. Many women find that online prescriptions via zoey™ are more cost-effective than repeated GP visits.
→ Return to pillar: Complete Guide to Birth Control in Singapore
This article is for informational purposes only and does not constitute medical advice. Always consult a licensed doctor before starting any contraception.

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